教授风采

 

 

 

一、基本情况

医学博士，教授（农学），研究员（医学），博士/硕士研究生导师、粮油深加工与品质控制湖南省重点实验室主任，林产可食资源安全与加工利用湖南省重点实验室副主任，湖南省食品科学技术学会常务理事、湖南省营养协会理事。曾先后在中南大学湘雅医学院、医学遗传学国家重点实验室工作了10年，法国国家科学研究中心（CNRS）转基因研究所分子病理研究室博士后工作了2年，英国剑桥大学病理系工作了10年，共发表论文200多篇，SCI论文160多篇，包括国际著名期刊：Oncogene、PNAS、J Pathol、Shock、Exp Cell Res、Mol Nutr Food Res、J Agric Food Chem、Food & Funct、J Funct Foods、Nutrients、Trends Food Sci Tech、Crit Rev Food Sci Nutr、Compr Rev Food Sci Food Saf. Crit Rev Biotechnol、Trends Food Sci Tech等。在剑桥大学，参与了3项课题（Wellcome Trust 和 Cancer Research UK）的申请与研究。在国内，作为课题负责人获国家自然科学基金面上项目2项，国家重大专项子课题3项，作为研究骨干参与国家自然科学基金7项及多项国家重大研究课题包括“863”、“973”等。曾获国内省部级奖5项。

研究方向：食品营养与健康。评估食品及其活性成分降脂、抗疲劳、抗低氧、抗炎、抗衰老、抗氧化和抗癌等生物学功能及其分子机理的研究，开发相关功能性食品。

招生学科/领域：77779193永利官网、生物与医药、

联系方式：T20121480@csuft.edu.cn

 

二、工作与学习经历

2012.12~至今          77779193永利官网77779193永利官网学院 研究员、教授

2010.07~2012.10      英国剑桥大学生物医学研究所，Research Associate

2009.01~2010. 06      中南大学肿瘤研究所副研究员

2003.01~2009.01      英国剑桥大学病理系，Research Associate

2001.07~2003.01     法国国家科学研究中心（CNRS）转基因研究所 博士后1998.08~2001. 07      中南大学肿瘤研究所，博士

1995.09~1998. 07      中南大学病理生理系，硕士

1991.07~1995.08   中南大学医学遗传学国家重点实验室，助理研究员

 

三、主持的科研项目（课题）

1. 主持，国家自然科学基金项目：项目名称：EB病毒LMP1激活的信号传导通路间cross-talk 的机理研究。

项目批准号：30000087

2. 主持，国家自然科学基金面上项目：基于分子影像技术建立可视化的鼻咽癌肿瘤转移模型，项目批准号：81071755

3. 子课题主持，国家自然科学基金重点项目：通过模式识别受体诱导的炎症反应及其在鼻咽癌发生发展中的机制研究，项目批准号：91129709

4. 子课题主持，国家十四五重大专项：动物源功能物质挖掘和生物活性作用机制。项目批准号：2022YFF1100200

5. 主持，湖南省自然科学基金，持续高脂饮食对小鼠后代的影响及其跨代传递的分子机理。项目批准号：2018JJ2672

 

四、主要奖励

1. 湖南2003年科学技术进步医学类一等奖，EB病毒潜伏膜蛋白1介导的信号转导通路异常激活在鼻咽癌变中的意义。登记号：943J20030013，单位名称：中南大学湘雅医学院肿瘤研究所。排名第三(3/10)

2. 2006年教育部科学技术奖自然科学奖二等奖，EB病毒潜伏膜蛋白1介导的信号转导通路异常激活在鼻咽癌变中意义。排名第四(4/12)

3．2003年教育部科学技术奖自然科学奖二等奖，细胞周期调节失控在鼻咽癌发病中的意义研究。排名第六

4．2013年湖南省科学技术奖一等奖，大米主食制品生产关键技术创新与产业化。排名第六

 

五、代表性成果

近5年代表性论文：

[1] Feijun Luo（共同通讯作者）et al.An active peptide from yak inhibits hypoxia-induced lung injury via suppressing VEGF/MAPK/inflammatory signaling. Redox Biology. 2024 Jun 22;75:103252. (中科院一区，Top期刊)

[2] Feijun Luo（通讯作者）et al.Network pharmacology combined with molecular docking and molecular dynamic simulation to reveal the potential mechanism of lentinan ameliorating hyperlipidemia. Food Bioscience 2024, 60: 104306  (中科院一区)

[3] Feijun Luo（共同通讯作者）et al.A peptide from yak ameliorates hypoxia-induced kidney injury by inhibiting inflammation and apoptosis via Nrf2 pathway. Food Bioscience 2024, 60: 104407.  (中科院一区)

[4] Feijun Luo（共同通讯作者）et al.Parboiled rice supplementation alleviates high-fat diet-induced hyperlipidemia by regulating genes and gut microbiota in mice. Food Science and Human Wellness 13 (2024).  (中科院一区)

[5] Feijun Luo（通讯作者）et al.Whole grain germinated brown rice intake modulates the gut microbiota and alleviates hypertriglyceridemia and hypercholesterolemia in high fat diet-fed mice.Food &Function. 2024 Jan 2;15(1):265-283.  (中科院一区，Top期刊)

[6] Feijun Luo（共同通讯作者）et al.[3].Extraction, structures, biological effects and potential mechanisms of Momordica charantia polysaccharides: A review. International Journal of Biological Macromolecules, 2024,  (中科院一区)

[7] Feijun Luo（共同第一作者）et al.Discovery and mechanism of anti-hypertensive effect of a novel tripeptide (SYP) from medicinal fungus Ganoderma lingzhi. Food Science and Human Wellness, April 2024, DOI: 10.26599/FSHW.2024.9250032  (中科院一区)

[8] Feijun Luo（通讯作者）et al.Targeting the Nrf2 signaling pathway by bioactive peptides to alleviates oxidative stress-associated diseases. Food Science and Human Wellness, April 2024, DOI: 10.26599/FSHW.2024.9250053 (中科院一区)

[9] Feijun Luo（共同通讯作者）et al.Exploration on anti-hypoxia properties of peptides: a review. Review. Critical Reviews in Food Science and Nutrition, 2023 Dec 20:1-16.  (中科院一区，Top期刊)

[10] Feijun Luo（通讯作者）et al.Targeting gut-brain axis by dietary flavonoids ameliorate aging-related cognition decline: Evidences and mechanisms. Critical Reviews in Food Science and Nutrition, 2023 Jun 10:1-22. (中科院一区，Top期刊)

[11] Feijun Luo（通讯作者）et al.Targeting AMPK signaling by polyphenols: a novel strategy for tackling aging. Food &Function. 2023 Jan 3;14(1):56-73. (中科院一区，Top期刊)

[12] Feijun Luo（通讯作者）et al.Targeting gut-liver axis by dietary lignans ameliorate obesity: evidences and mechanisms. Critical Reviews in Food Science and Nutrition, 2023:1-22.  (中科院一区，Top期刊)

[13] Feijun Luo（通讯作者）et al.Polysaccharides from Phellinus linteus: A systematic review of their extractions, purifications, structures and functions. International Journal of Biological Macromolecules, 2023 Mar 1:230:123163. (中科院一区)

[14] Feijun Luo（通讯作者）et al.Targeting mTOR Signaling by Dietary Polysaccharides in Cancer Prevention: Advances and Challenges. Journal of Agricultural Food Chemistry. 2022 Dec 21. (中科院一区，Top期刊)

[15] Feijun Luo（通讯作者）et al.Dietary flavonoids prevent diabetes through epigenetic regulation: advance and challenge. Critical Reviews in Food Science and Nutrition, 2022 Jul 11:1-17.  (中科院一区，Top期刊)

[16] Feijun Luo（共同通讯作者）et al.[3].Oryzanol Attenuates High Fat and Cholesterol Diet-Induced Hyperlipidemia by Regulating the Gut Microbiome and Amino Acid Metabolism. Journal of Agricultural Food Chemistry. 2022 Jun 1;70(21):6429-6443.  (中科院一区，Top期刊)

[17] Feijun Luo（共同通讯作者）et al.Oryzanol alleviates high fat and cholesterol diet-induced hypercholesterolemia associated with the modulation of the gut microbiota in hamsters. Food &Function, 2022 Apr 20;13(8):4486-4501. (中科院一区，Top期刊)

[18] Feijun Luo（共同通讯作者）et al.[3].Biological functions of active ingredients in quinoa bran: Advance and prospective. Critical Reviews in Food Science and Nutrition, 2022 Oct 31:1-15.  (中科院一区，Top期刊)

[19] Feijun Luo（通讯作者）et al.Dietary flavonoids prevent diabetes through epigenetic regulation: advance and challenge.Critical Reviews in Food Science and Nutrition, 2023, 63:33, 11925-11941.  (中科院一区，Top期刊)

[20] Feijun Luo（共同通讯作者）et al.Targeting NF-κB pathway by dietary lignans in inflammation: expanding roles of gut microbiota and metabolites.Critical Reviews in Food Science and Nutrition, 2022 Jan 24:1-17. (中科院一区，Top期刊)

[21] Feijun Luo（共同通讯作者）et al.Dietary Supplementation of Octacosanol Improves Exercise-Induced Fatigue and Its Molecular Mechanism.Journal of Agricultural Food Chemistry. 2021 Jul 14;69(27):7603-7618. (中科院一区，Top期刊)

[22] Feijun Luo（共同通讯作者）et al.Oryzanol alleviates high fat and cholesterol diet-induced hypercholesterolemia associated with the modulation of the gut microbiota in hamsters. Food &Function. 2022 Mar 29.  (中科院一区，Top期刊)

[23] Feijun Luo（通讯作者）et al.Targeting AMPK Signaling by Dietary Polyphenols in Cancer Prevention. Mol Nutr Food Res. 2022 Jan;66(2):e2100732. doi: 10.1002/mnfr.202100732 (中科院一区)

[24] Feijun Luo（共同通讯作者）et al.Dietary polysaccharides exert biological functions via epigenetic regulations: Advance and prospectives. Critical Reviews in Food Science and Nutrition, (中科院一区，Top期刊)

[25] Feijun Luo（共同通讯作者）et al.Gastrodin ameliorates exercise-induced fatigue via modulating Nrf2 pathway and inhibiting inflammation in mice. Food Bioscience 51 (2023) 102262 (中科院一区)

[26] Feijun Luo（共同通讯作者）et al.You are affected by what your parents eat: Diet, epigenetics, transgeneration and intergeneration. Trends in Food Science & Technology, 2020, 100: 248–261. (中科院一区，Top期刊)

[27].Feijun Luo（共同通讯作者）et al.δ-Tocotrienol induces apoptosis and inhibits proliferation of nasopharyngeal carcinoma cells. Food & Function, 31 May 2021, DOI: 10.1039/d1fo00461a (中科院一区，Top期刊)

[28].Feijun Luo（共同通讯作者）et al.A novel 14-amino acid peptide from yak alleviates kidney damage in the rat model of myocardial ischemia-reperfusion. Food Bioscience, 2024, 58: 103719.  (中科院一区)

[29].Feijun Luo（通讯作者）et al.Targeting Nrf2 by bioactive peptides alleviate inflammation: expanding the role of gut microbiota and metabolites.Critical Reviews in Food Science and Nutrition, 2024 Jun 17:1-20.(中科院一区，Top期刊)

 

六、主要讲授课程

本科生课程：《食品生物技术》、《食品科技论文写作》

硕士研究生课程《高级食品生物技术》、《食品生物技术案例》

博士研究生课程《天然产物的生物学功能评估》